The CW has released the Official Synopsis of Supergirl episode “O Brother, Where Art Thou?” (4.15) that will be aired Sunday, March 17 at 08:00-09:00 PM.
JON CRYER GUEST STARS AS ICONIC DC COMICS’ VILLAIN LEX LUTHOR
Secretly furloughed from prison due to failing health, Lex Luthor (guest star Jon Cryer) visits his sister, Lena (Katie McGrath), to seek her help finding a cure. Savvy as ever, Lena is suspicious of Lex’s motives but when she’s faced with a life and death situation, she must decide how she truly feels about her brother. Meanwhile, Supergirl (Melissa Benoist) and J’onn (David Harewood) face off against Manchester Black (guest star David Ajala). James’ sister Kelly (guest star Azie Tesfai) comes to town.
SUPERGIRL stars Melissa Benoist as Kara Danvers/Supergirl, Chyler Leigh as Alex Danvers, Mehcad Brooks as James Olsen, David Harewood as Hank Henshaw, Jeremy Jordan as Winslow “Winn” Schott and Tyler Hoechlin as Superman.
Supergirl is an action-adventure drama based on the DC Comics character Kara Zor-El (Melissa Benoist), Superman’s (Kal-El) cousin who, after 12 years of keeping her powers a secret on Earth, decides to finally embrace her superhuman abilities and be the hero she was always meant to be.
Based on characters appearing in comic books and graphic novels published by DC Comics, with executive producers Greg Berlanti, Ali Adler, Sarah Schecter and Andrew Kreisberg for Berlanti Productions in association with Warner Bros. Television.